| 锰、铋共掺杂铌酸钠压电效应促进细胞增殖及抗菌 | |
| Piezoelectric effect of Mn, Bi co-doped sodium niobate for promoting cell proliferation and bacteriostasis | |
| 摘要: 通过水热法制备了锰、铋共掺杂铌酸钠压电骨修复材料。通过扫描电镜、X射线衍射仪、X射线光电子能谱仪、压电力显微镜、电化学工作站、紫外可见近红外光谱仪、电子顺磁共振波谱仪等对该材料的微观形貌、组成结构、压电性能、声动力性能和类酶活性等进行表征。结果表明，该材料兼具压电性能和类酶活性，超声触发压电响应不仅促进细胞增殖，而且增强声动力和类酶活性，产生活性氧，协同杀死细菌/清除生物膜。 | |
| 关键词: 压电效应 声动力 类酶活性 细胞增殖 抗菌 | |
| 基金项目: 国家自然科学基金(No.32171340)资助。 | |
| Abstract: A bone repair material of Mn, Bi co-doped sodium niobate with piezoelectricity was prepared using the hydrothermal method. The microscopic morphology, composition, piezoelectricity, sonodynamic and enzyme-like activity of the material was characterized by scanning electron microscope, X-ray diffractometer, X-ray photoelectron spectrometer, piezoelectric force microscope, electrochemical workstation, ultraviolet-visible-near-infrared spectrometer, and electron paramagnetic resonance spectrometer. The results demonstrate that the material possesses both piezoelectric properties and enzyme-like activity; the ultrasound-triggered piezoelectric effect not only promotes cell proliferation but also enhances sonodynamic and enzyme-like activity, which generates reactive oxygen species for synergistic killing of bacteria/removal of biofilm. | |
| Keywords: piezoelectricity sonodynamic enzyme-like activity cell proliferation antibacterial | |
| 投稿时间：2024-03-25 修订日期：2024-08-24 | |
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| 王世鹏,解尚谕,梁露娴,王雪红,魏杰,王德强.锰、铋共掺杂铌酸钠压电效应促进细胞增殖及抗菌[J].无机化学学报,2024,40(10):1919-1931. | |
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