| 高密度自由羧基氧修饰孔壁的锌基金属有机骨架靶向电化学传感对乙酰氨基酚 | |
| Zinc metal-organic framework with high-density free carboxyl oxygen functionalized pore walls for targeted electrochemical sensing of paracetamol | |
| 摘要: 基于刚性苯多羧酸H4BPTC (联苯-3，3'，5，5'-四甲酸)，构筑了一例孔壁修饰高密度自由羧基氧的三维刚性锌基金属有机骨架：{[Zn2(BPTC)(H2O)(DMF)2]·DMF·H2O}n(SXNU-5-Zn)。SXNU-5-Zn具有好的酸碱稳定性(pH=3~8)和热稳定性。以SXNU-5-Zn构建了基于纯MOFs材料的电化学传感器(SXNU-5-Zn/GCE)，其可高灵敏、选择性的检测对乙酰氨基酚(AC)，检测的线性范围宽(0.02~765 μmol·L-1)，检测限低至0.013 8 μmol·L-1(S/N=3)。此外，所制备的SXNU-5-Zn/GCE传感器已成功应用于实际样品复方对乙酰氨基酚片中AC含量的检测。 | |
| 关键词: 金属有机骨架 锌 电化学传感器 对乙酰氨基酚 | |
| 基金项目: 运城市科技局基础研究项目（No.YCKJ-2020065）资助。 | |
| Abstract: Based on the rigid benzene polycarboxylic acid H4BPTC (biphenyl-3,3',5,5'-tetracarboxylic acid),a 3D rigid zinc-based metal-organic framework with high-density free carboxyl oxygen modified pore walls,{[Zn2(BPTC)(H2O)(DMF)2]·DMF·H2O}n(SXNU-5-Zn),has been constructed.SXNU-5-Zn exhibited good acid-base stability within a pH range of 3-8 and excellent thermal stability.An electrochemical sensor,SXNU-5-Zn/GCE,based on a pure MOF material was constructed,which can detect paracetamol (AC) with high sensitivity and selectivity.The linear detection range spans from 0.02 to 765 μmol·L-1,with a limit of detection as low as 0.013 8 μmol·L-1(S/N=3).Furthermore,the prepared SXNU-5-Zn/GCE sensor has been successfully utilized to determine the AC content in compound acetaminophen tablets as an actual sample. | |
| Keywords: metal-organic framework zinc electrochemical sensor paracetamol | |
| 投稿时间：2023-11-14 修订日期：2024-01-30 | |
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| 续璐,张丞雨,籍文娟,杨海英,付云龙.高密度自由羧基氧修饰孔壁的锌基金属有机骨架靶向电化学传感对乙酰氨基酚[J].无机化学学报,2024,40(5):907-918. | |
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