| 含异恶唑二铁配合物的合成、表征及电催化产氢性能和抗菌活性 |
| Synthesis, characterization, electrocatalytic properties, and antifungal activity of isoxazole-containing di-iron complexes |
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| 摘要: 本文报道了4个含异恶唑基团的二铁配合物的制备及其结构表征。以含羟基二铁配合物[Fe2（CO）6（μ-SCH2CH（CH2OH）S）] （1）与5-甲基异恶唑-4-羧酸为原料，经过酯化反应以高产率制备了配合物[Fe2（CO）6（μ-SCH2CHCH2OOC（5-C3HNOCH3）S）] （2），再分别与三（对甲苯基）膦、三（4-氟苯基）膦或三（2-甲氧基苯基）膦反应，合成了3个含膦配合物[Fe2（CO）5（L）（μ-SCH2CHCH2OOC（5-C3HNOCH3）S）]，其中L=P（4-C6H4CH3）3 （3）、P（4-C6H4F）3 （4）、P（2-C6H4OCH3）3 （5）。使用元素分析、谱学和X射线晶体学对新配合物的结构进行了表征。电化学性质研究表明这些配合物可以催化醋酸中的质子还原产生氢气。其中，2拥有最低的过电位而4拥有最高的催化效率。此外，该类配合物还具有一定的抗菌活性。 |
| 关键词: 二铁配合物 异恶唑 X射线晶体学 电化学 抗菌活性 |
| 基金项目: 浙江省自然科学基金（No.LY19B020002）、钒钛资源综合利用四川省重点实验室项目（No.2021FTSZ07）、化学合成与污染控制四川省重点实验室项目（No.CSPC201904）、四川省人社厅项目、自贡人才计划（2019）和四川轻化工大学项目（No.202310622010，Y2023062）和浙江三赢新材料有限公司项目（No.KYY-HX-20210140，KYY-HX-20200746）资助 |
| Abstract: In this paper, four di-iron complexes with an isoxazole moiety were synthesized and characterized. The reaction of a hydroxy-containing di-iron complex [Fe2(CO)6(μ-SCH2CH(CH2OH)S)] (1) with 5-methylisoxazole-4-carboxylic acid gave an ester product, named [Fe2(CO)6(μ-SCH2CHCH2OOC(5-C3HNOCH3)S)] (2) in very good yield. The phosphine-bearing analogues, which are named [Fe2(CO)5(L)(μ-SCH2CHCH2OOC(5-C3HNOCH3)S)] where L= P(4-C6H4CH3)3 (3), P(4-C6H4F)3 (4), P(2-C6H4OCH3)3 (5), were prepared by the reactions of complex2 with a monophosphine ligand tri(p-tolyl)phosphine, tris(4-fluorophenyl)phosphine or tris(2-methoxyphenyl)phosphine. Complexes2-5 have been identified by elemental analyses, spectroscopies, and X-ray crystallography. The electrochemical properties were probed by cyclic voltammetry, which shows that these complexes can catalyze the production of dihydrogen with acetic acid as a proton source.2 had the lowest overpotential and4 had the highest catalytic efficiency. Moreover, we have investigated the antifungal activity of these new complexes. |
| Keywords: di-iron complex isoxazole X-ray crystallography electrochemistry antifungal activity |
| 投稿时间：2023-08-03 修订日期：2023-11-06 |
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| 刘旭锋,李玉龙,刘幸海.含异恶唑二铁配合物的合成、表征及电催化产氢性能和抗菌活性[J].无机化学学报,2023,39(12):2367-2376. |
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