| 烟酰胺腺嘌呤二核苷酸磷酸与纳米氧化铝和勃姆石的作用(英文) | |
| Interactions of Nicotinamide Adenine Dinucleotide Phosphate with Nano-Boehmite and Nano-Corundum | |
| 摘要: 采用多种现代分析手段研究了烟酰胺腺嘌呤二核苷酸磷酸(NADP+)与纳米氧化铝(γ-Al2O3)和纳米勃姆石(γ-AlOOH)的相互作用，结果显示NADP+与γ-AlOOH 主要通过静电作用相结合，而在γ-Al2O3表面除了静电和氢键作用外，还存在通过铝与磷酸根中的氧配位形成的内层配合物；在3＜pH＜5时，NADP+的最大吸附量明显下降，这可能是由于酸性条件下溶解Al(Ⅲ)的竞争吸附所致；NADP+与2种纳米铝化合物的吸附过程均为自发的，且符合Langmuir等温式。荧光结果表明吸附后NADP+折叠式构象增加，由此可能影响依赖于NADP+的脱氢酶体系的生物活性。 | |
| 关键词: 吸附 纳米氧化铝 纳米勃姆石 烟酰胺腺嘌呤二核苷酸磷酸 | |
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| Abstract: The adsorption behavior of NADP+ on the nano-boehmite (γ-AlOOH) and nano-corundum (γ-Al2O3) surfaces was examined using batch adsorption experiments over a broad range of NADP+ concentrations and pH values. The results indicate that NADP+ is predominantly adsorbed on the boehmite surface as an outer-sphere by electrostatic interaction via NADP+ phosphate and surface hydroxyl groups over the investigated pH values. In contrast, on the corundum surface, two outer-sphere complexes are formed by the electrostatic force and the hydrogen bond in all cases, and another minor inner-sphere complex involving the phosphate is formed at low pH values. However, at 3＜pH＜5, the extent of NADP+ adsorption falls significantly below the expected value. This can be interpreted in terms of competitive adsorption of dissolved Al(Ⅲ) with NADP+ under acidic conditions. Moreover, the adsorption behavior on the two nano-aluminum compounds could be well fitted with the ideal Langmuir isotherms and both of them are spontaneous. The adsorption might influence the activity of NADP+-specific dehydrogenase in the biological system. | |
| Keywords: adsorption nicotinamide adenine dinucleotide phosphate nano-corundum nano-boehmite | |
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| 李 丽,汤勇铮,李卉卉,杨绪杰,陆天虹,杨小弟.烟酰胺腺嘌呤二核苷酸磷酸与纳米氧化铝和勃姆石的作用(英文)[J].无机化学学报,2013,29(1):111-122. | |
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