| 一维链状配位聚合物乙醇合二丁基锡-3，5-二硝基-2-氧苯甲酸酯的合成、结构和性质 |
| Synthesis, Structure and Property of One-Dimension Chain Coordination Polymer (Ethanol)dibutyltin 3,5-Dinitro-2-oxybenzoate |
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| 摘要: 利用二丁基氧化锡和3，5-二硝基水杨酸在苯-乙醇中反应合成了新配合物乙醇合二丁基锡3，5-二硝基-2-氧苯甲酸酯(n-C4H9)2Sn(2-O-3，5-(NO2)2C6H2COO)(C2H5OH) (1)，通过元素分析、IR、1H NMR和X-射线单晶衍射表征了其结构。化合物1属单斜晶系，P21/c空间群，a=1.363 33(10) nm，b=1.861 90(14) nm，c=0.841 51(6) nm，β=93.311(1)°，Z=4，V=2.132 5(3) nm3，R1=0.033 6，wR2=0.090 0。该化合物为由羧基桥联配位和分子间氢键形成的新型一维链状有机锡配合物，锡原子具有六配位[SnC2O4]畸变八面体构型。化合物1对2种人癌细胞A549和CoLo205增殖均有强的抑制作用，对乙酰乙酸乙酯与醇的酯交换反应具有高选择性和良好的催化活性。 |
| 关键词: 有机锡羧酸酯 3，5-二硝基水杨酸 晶体结构 抗癌活性 催化 |
| 基金项目: |
| Abstract: A novel organotin complex (ethanol)dibutyltin 3,5-dinitro-2-oxybenzoate, (n-C4H9)2Sn(2-O-3，5-(NO2)2C6H2COO)(C2H5OH) (1), has been prepared by the reaction of dibutyltin oxide and 3,5-dinitrosalicylic acid in the benzene-ethanol and characterized by elemental analysis, IR, 1H NMR and X-ray single crystal diffraction. The crystal for 1 belongs to monoclinic space group P21/c with a=1.363 33(10) nm, b=1.861 90(14) nm, c=0.841 51(6) nm, β=93.311(1)°, Z=4, V=2.132 5(3) nm3, R1=0.033 6, wR2=0.090 0. The compound 1 is a novel one-dimension chain coordination polymer formed by the bridged coordination of carboxyl group and intermolecular hydrogen bond, and tin atom possesses a distorted [SnC2O4] octahedral geometry. The compound display strong in vitro anti-tumor activity against two human tumor cell lines, A549 and CoLo205, and high selectivity and good catalysis activity on the transesterification reaction of ethyl acetoacetate with an alcohol. CCDC: 797927. |
| Keywords: organotin carboxylate 3,5-dinitrosalicylic acid crystal structure anti-tumor activity catalysis |
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| 田来进,赵燕翔,郑晓亮,董 杰,颜冬梅,屠凌岚.一维链状配位聚合物乙醇合二丁基锡-3，5-二硝基-2-氧苯甲酸酯的合成、结构和性质[J].无机化学学报,2010,26(12):2165-2169. |
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