| 银离子配位色谱法分离香茅次油中β-榄香烯的研究 |
| Isolation of β-Elemene from Citronella Oil by Silver Ion Coordination Chromatography |
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| 摘要: 目的：对比硅胶与硝酸银硅胶层析介质对β-榄香烯的吸附及分离效果，从香茅次油中分离得到β-榄香烯。方法：测定β-榄香烯银离子配位化合物的稳定常数，考察不同极性溶剂中β-榄香烯在硅胶及硝酸银硅胶表面的静态吸附情况，香茅次油在两种层析介质中的薄层分离情况，并采用柱层析方法分离β-榄香烯。结果：β-榄香烯与硝酸银能够形成π配位化合物，稳定常数为5.12×10-5 L·mol-1；当硅胶作为层析介质时，β-榄香烯静态吸附量较小，符合单分子层吸附模型，溶剂极性增大有利β-榄 |
| 关键词: β-榄香烯 银离子配位色谱 分离 |
| 基金项目: |
| Abstract: Aim: To separate β-elemene from other sesquiterpenes, and compare the effect of silica gel chromatography with/without silver nitrate modification. Methods: Detecting the complex constant of β-elemene-Ag+ coordination compound, and investigating the static adsorption of β-elemene on silica gel before and after treated with silver nitrate in different polar solution and the thin layer chromatography of citronella oil when silica gel and silver nitrate modified silica gel are used for chromatography medium, and separating β-elemene from other sesquiterpenes by silica gel and silica gel column chromatography modified with silver nitrate. Results: β-Elemene-Ag+ pi coordination compound will be formed with stability constant 5.12×10-5 when silver nitrate is added to β-elemene solution. When silica gel is treated as medium, the adsorption of β-elemene conforms to the Langmuir monomolecular adsorption theory and the adsorbility is weak. The polar solvent is available to separate β-elemene from other sesquiterpenes, but the separating result is not good. The 97% content of β-elemene accounts for 11 percent of recovery. While silica gel modified with silver nitrate is treated as medium, the adsorption of β-elemene conforms to BET adsorption theory and the adsorbility is strong. The middling polar solvent is acceptable, and the 98% content of β-elemene accounts for 60 percent of recovery. Conclusions: The selective adsorption of β-elemene will be increased when silica gel is modified by silver nitrate, and the stability of different structure sesquiterpenes-Ag+ coordination compounds is related to their molecular structure and solvents. Conventional silica gel chromato-graphy can not be available to separate sesquiterpenes. However, β-elemene can be isolated high efficiently from sesquiterpenes mixtures by silica gel chromatography modified with silver nitrate. |
| Keywords: β-elemene silver ion coordination chromatography isolation |
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| 黄汉昌,朱宏吉,姜招峰.银离子配位色谱法分离香茅次油中β-榄香烯的研究[J].无机化学学报,2009,25(3):433-438. |
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