| 基于2-(2′-吡啶基)苯并咪唑的Zn2+比例计量型荧光识别 | |
| Ratiometric Sensing of Zn2+ by 2-(Pyridin-2′-yl)-1H-benzo[d]imidazole | |
| 摘要: 本文以荧光分子2-(2′-吡啶基)苯并咪唑(2-PBI)作为1，1′-联(2-芳杂环)类化合物模型，研究利用其2，2′-N原子螯合Zn2+诱导芳环共面化和荧光发射红移实现Zn2+比例计量检测的可行性。2-PBI在不同体系中的Zn2+荧光响应行为表明Zn2+结合将导致最大发射波长明显红移(乙腈36 nm；HEPES缓冲液39 nm)，具有比例计量型Zn2+荧光探针的基本特点。2-PBI还具有显著的Z | |
| 关键词: 锌离子 荧光 比例计量型探针 | |
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| Abstract: 2-(Pyridin-2′-yl)-1H-benzo[d]imidazole (2-PBI) was used as a fluorophore/ionophore model of 1,1′-bi(2-heteroaromatic) compounds to explore the possibility for ratiometric Zn2+ determination by the co-planation of the two heteroaromatic rings via Zn2+-chelation with 2,2′-N atoms. Investigation in different media shows the evident Zn2+-triggered red-shifted emission (36 nm in acetonitrile and 39 nm in neutral buffer), meeting the essential requirement of ratiometric sensors. Moreover, 2-PBI still displays distinct selectivity for Zn2+ without introducing special fluorophore. All these make 2-PBI a potential candidate for being both fluorophore and ionophore to construct Zn2+ ratiometic sensors through a mechanism of Zn2+-chelation induced co-planation of biheteroaromatic rings. Moreover, analysis of its emission mechanism and Zn2+-sensing behavior give further clues that 2-PBI could become a practical fluorescent sensors for ratiometric detection of Zn2+. | |
| Keywords: zinc fluorescence ratiometric fluorescent sensor | |
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| 万丹丹,苏光余,许子华,张玉明,吴正轶,何卫江,郭子建.基于2-(2′-吡啶基)苯并咪唑的Zn2+比例计量型荧光识别[J].无机化学学报,2008,24(8):1253-1260. | |
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