| 6-苄氨基嘌呤及其金属配合物与DNA的作用机理 |
| The Action Mechanism of 6-Benzyl-amino-purine and Its Metal Complexes with DNA |
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| 摘要: |
| 关键词: 6-苄氨基嘌呤金属配合物 DNA Scatchard 图 |
| 基金项目: |
| Abstract: The mechanism for interactions of the 6-benzyl-amino-purine and its CO2+, Ni2+ complexes with DNA was studied by UV and fluorescence spectra using ethidium bromide (EB) as probe molecule. When pH=7.4, the action of 6-benzyl-amino-purine-CO2+ and DNA was electrostatic effect and certain kind of intercalation action; when pH=9.86, the action of the two was electrostatic effect; when pH=2.85 , the action of 6-benzyl-amino-purine-Ni2+ and DNA was both electrostatic and intercalation action. But when pH=7.4, 6-benzyl-amino-purine hardly influenced the intercalation action of EB and DNA, the action of 6-benzyl-amino-purine and DNA was electrostatic action. |
| Keywords: 6-benzyl-amino-purine metal complex DNA scatchard plots |
| 投稿时间：2005-03-13 修订日期：2005-06-21 |
| 摘要点击次数: 1221 |
| 全文下载次数: 1867 |
| 席小莉,杨曼曼,杨频.6-苄氨基嘌呤及其金属配合物与DNA的作用机理[J].无机化学学报,2005,21(12):1847-1852. |
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