| 制备抗肿瘤药物庚铂的新方法 |
| A Novel Approach for Preparing the Anti-Tumor Drug: Sunpla |
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| 摘要: |
| 关键词: 庚铂 抗肿瘤药物 铂配合物 制备方法 波谱表征 |
| 基金项目: |
| Abstract: Sunpla (SKI2053R), an anti-tumor drug in clinic use, has been prepared by a new method in which mercurous ions instead of silver ones were used to remove the coordinating halide anions from the intermediate, [R(-NH2)2PtX2], and alkaline earth cations malonate or ammonium malonate were applied in the synthesis. The resulting platinum(Ⅱ) complex has been characterized with its IR, 1H-NMR and 13C-NMR, FAB-MS and TG-DTA spectra. |
| Keywords: sunpla anti-tumor drug platinum(Ⅱ) complex preparation spectral characterization |
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| 吴玉霞,陈永江,周云曙,袁开红,苟少华.制备抗肿瘤药物庚铂的新方法[J].无机化学学报,2004,20(2):215-218. |
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