无机化学学报

水溶性[5-邻(乙氧羰基甲氧基苯基)-10,15,20-Tri(4-N-甲基吡啶基)]卟啉铜(Ⅱ)配合物的合成、表征及其和单核苷酸的相互作用

Synthesis, Characterization and Interaction with Mononucleotide of [5-o(ethoxycarbonyl methoxyphenyl)-10,15,20-Tris(4-N-methylpyridiniumyl) Porphyrinato]copper(Ⅱ)

作者	单位
韩高义	南京大学化学系, 南京大学配位化学国家重点实验室, 南京 210093 山西大学分子科学研究所太原 030006
杨频	山西大学分子科学研究所太原 030006

摘要: 合成并表征了[5-o-(乙氧羰基甲氧基苯基)-10,15,20-Tri(4-N-甲基吡啶基)]卟啉H₂[(5-o-(Emoph)-Tri(4-N-Mepy)]PP(1)及其铜配合物Cu[(5-o-(Emoph)-Tri(4-N-Mepy)]PP(2),用紫外可见光谱滴定法测定了配合物(2)与单核苷酸的配位平衡常数,研究了它作为主体分子和单核苷酸的相互作用。研究结果表明,各配体结合常数按K(dGMP)>K(dAMP)>K(dTMP)>K(dCMP)≥K(dUMP)的顺

关键词: [5-o-(乙氧羰基甲氧基苯基)-10,15,20-Tri(4-N-甲基吡啶基)]卟啉铜单核苷酸 π-π配合

基金项目: 国家自然科学基金(No.29871020)

Abstract: 5-[o-(ethoxylcarbonyl methoxyphenyl)-10,15,20,Tris(N-4-methylpyridiniumyl)]Porphyrin(1) and its copper(Ⅱ) derivative(2) were synthesized and characterized by means of spectrophotometer technique. The equilibrium constant of theππ coordination reaction were measured between 2 and mononucleotide and tryptophan by using UV Vis titriation method. The results show that the equilibrium constants decrease in the order of K(dGMP) >K(dAMP) >K(dTMP)> K(dCMP)≥ K(dUMP). The thermodynamic parameters of the complexation reaction were also determined, the results show that the coordination reaction is an exothermal and entropy lose process and the phenomena of enthalpy entropy compensation was observed.

Keywords: 5-[o-(ethoxylcarbonyl methoxyphenyl-10,15,20-tris(4-N-ethylpyridiniumyl) porphyrinato] copper mononucleotide π-π complexation

投稿时间：2000-06-15 修订日期：2000-08-17

摘要点击次数: 1157

全文下载次数: 1518

韩高义,杨频.水溶性[5-邻(乙氧羰基甲氧基苯基)-10,15,20-Tri(4-N-甲基吡啶基)]卟啉铜(Ⅱ)配合物的合成、表征及其和单核苷酸的相互作用[J].无机化学学报,2000,16(6):928-932.

查看全文查看/发表评论下载PDF阅读器

Support information: