二价铜、锌离子对盐酸巴马亭与牛血清白蛋白结合反应光谱的影响研究 |
SPECTROSCOPIC STUDIES ON BINDING OF PALMATINE HYDROCHLORIDE TO BOVINE SERUM ALBUMIN INFLUENCED BY ZINC(Ⅱ) AND COPPER (Ⅱ) |
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摘要: |
关键词: 盐酸巴马亭 牛血清白蛋白 铜离子 锌离子 光谱 |
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Abstract: The binding of Palmatine hydrochloride to bovine serum albumin (BSA) was studied, in the presence of Cu2+ and Zn2+, with fluorescence spectrum and ultra-violet spectrum. The results show that Cu2+ and Zn2+ don′t influence the first binding constant of Palmatine to BSA and the binding site of it to BSA. But Cu2+ has the fluorescence quenching effect on sensitive fluorescence of medicine binding to BSA. |
Keywords: Palmatine hydrochloride bovine serum albumin Cu2+ Zn2+ spectrum |
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张立伟,杨频,王芳.二价铜、锌离子对盐酸巴马亭与牛血清白蛋白结合反应光谱的影响研究[J].无机化学学报,1999,15(4):545-548. |
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