| 2，4-二羟基苯甲醛缩硫脲及其配合物的合成与生物活性研究 |
| SYNTHESIS, CHARACTERIZATION AND ANTIFUNGAL ACTIVITY OF 2,4-DIHYDROXYBENZALDEHYDE THIOCARBOHYDRAZONE AND THEIR COMPLEXES OF Cu(Ⅱ)、 Zn(Ⅱ) AND Ni(Ⅱ) |
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| 摘要: 合成了标题席夫碱及其Cu(Ⅱ)、 Zn(Ⅱ)、 Ni(Ⅱ)配合物，对它们进行了元素分析、UV、IR，对配体进行了质谱和 1H NMR等结构表征。还对化合物进行了抑制超氧阴离子自由基及消灭钉螺的生物活性研究。 |
| 关键词: 2，4-二羟基苯甲醛缩硫脲 铜(Ⅱ) 锌(Ⅱ) 镍(Ⅱ) 钉螺 |
| 基金项目: |
| Abstract: 2,4-dihydroxybenzaldehyde thiocarbohydrazone (C15H12N2O4S)and their complexes of copper(Ⅱ)、 zinc (Ⅱ) and nickel(Ⅱ) have been synthesized and characterized by elemental analysis, electronic absorption spectrum, IR, and molar conductivity. The Schiff base ligand has been further ascertained by 1HNMR and m.s. Spectra. The composition, coordination state and possible structures in these compounds are given. The tests of biological activity shows that complexes synthesized have scavenging effect on superoxide free radical similar SOD enzyme and these compounds are effective chemicals to kill oncomelania. |
| Keywords: 2,4-dihydroxybenzaldehyde thiourea copper(Ⅱ) zinc(Ⅱ) nickel(Ⅱ) oncomelania |
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| 摘要点击次数: 2617 |
| 全文下载次数: 1850 |
| 祝心德,党元林,王成刚,乐芝凤,吴自慎.2，4-二羟基苯甲醛缩硫脲及其配合物的合成与生物活性研究[J].无机化学学报,1997,13(1):68-72. |
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